Iranian Journal of Nursing and Midwifery Research1735-9066251202012277175ENAmol Faculty of Nursing and Midwifery, Mazandaran University of Medical Sciences, Sari, IranGraduate School of Education, University of Exeter, UKNursing Student, Student Research Committee, Mazandaran University of Medical Sciences, Sari, IranNursing Student, Student Research Committee, Mazandaran University of Medical Sciences, Sari, IranAmol Faculty of Nursing and Midwifery, Mazandaran University of Medical Sciences, Sari, IranDepartment of Geriatric Nursing, School of Nursing and Midwifery, Tehran University of Medical Sciences, Tehran, Iran2019122820191228<p class="abst"><strong>Background:</strong> Usually, the endotracheal tube cuff pressure is controlled by cuff pressure monitoring. However, the intermittent pilot-manometer connection and disconnection may cause a change in the adjusted pressure. This study aimed to investigate changes in the endotracheal tube cuff pressure using both manual and intermittent controls.</p><p class="abst"><strong>Materials and Methods:</strong> A semi-experimental within-subject design was conducted. Fifty-nine intubated patients in the Mazandaran Intensive Care Units (ICUs) participated through convenience sampling in 2018. In the control condition, first, the cuff pressure was adjusted in 25 cm H₂O then it was measured without manometer-pilot disconnection at 1 and 5 min intervals. In the intervention condition, cuff pressure was immediately adjusted in 25 cm H₂O then it was measured with manometer-pilot disconnection in the 1^st and 5^th minutes. Data analysis was performed using Independent <em>t</em>-test, Chi-square test, and Phi coefficient.</p><p class="abst"><strong>Results:</strong> The mean and Standard Deviation (SD) change of cuff pressure after 1 minute, from 25 cm H₂O, in the intervention condition was 20.22 (3.53) cm H₂O. The mean (SD) of this change in the control condition was 25.22 (3.39) cm H₂O. This difference was significant (<em>t</em>₁₁₆= 7.83, <em>p</em> &lt; 0.001, d = 1.44). The mean (SD) change of cuff pressure after 5 minutes, from 25 cm H₂O, in the intervention condition was 19.11 (2.98) cm H₂O. The mean (SD) of this change in the control condition was 25.47 (4.53) cm H₂O. This difference was significant (<em>t</em>₁₁₆= 9.24, <em>p</em> &lt; 0.001, d = 1.70).</p><p class="abst"><strong>Conclusions:</strong> The tracheal tube cuff pressure has been significantly reduced during manual intermittent measuring. Therefore, it is suggested that continuous cuff pressure monitoring and regulation should be used.</p><p class="kyds"><strong><br /></strong><em></em></p>http://ijnmr.mui.ac.ir/index.php/ijnmr/article/view/1689http://ijnmr.mui.ac.ir/index.php/ijnmr/article/download/1689/70707244