Iranian Journal of Nursing and Midwifery Research1735-906625420210618291295ENFaculty of Nursing, Sri Ramachandra Institute of Higher Education and Research (DU), Porur, Chennai, Tamil Nadu, India1Institute of Higher Education and Research (DU), Porur, Chennai, Tamil Nadu, IndiaDeptartment of Obstetric Nursing, Principal, Faculty of Nursing, Sri Ramachandra Institute of Higher Education and Research (Deemed to be University), Porur, Chennai, Tamil Nadu, IndiaDepartment of Medical Surgical Nursing, Principal,Vellammal College of Nursing, Madurai, Tamilnadu,India20200621<p><strong>Background: </strong>Buerger‑Allen Exercise (BAE) promote Lower Extremity Perfusion (LEP)  via the wound healing process and reduce Peripheral Neuropathy Symptoms (PNS) among  Diabetes Mellitus (DM) patients. We study the efficacy of BAE on LEP and PNS among patients with  DM.   </p><p><strong>Materials and Methods: </strong>This quasi‑experimental study was conducted prospectively from July  to October 2017. Fifty DM patients between the ages of 30 and 75 from both genders were selected  using a purposive sampling technique and were assessed for LEP with a manual Ankle‑Brachial  Index (ABI) scale and assessed for PNS with Michigan Neuropathy Screening Instrument (MNSI).  The BAE was demonstrated for 4 consecutive days. The intervention was repeated five times per  day for each patient and the posttest was conducted 5th day using the same tools.   </p><p><strong>Results: </strong>The  majority (<em>n </em>= 75, 75%) were 60–69 age group and 98% had education till primary school. 62% had  diabetes and 20% of them had a history of peripheral arterial disease. 50% of participants had mildly  impaired perfusion during pretest whereas abnormal neuropathy was seen in more than 70% cases  which decreased posttest. A significant difference in PNS was seen after the implementation of BAE  in both right LEP (t48 = 6.81, <em>p </em>&lt; 0.001) and left LEP t48 = 5.21, <em>p </em>&lt; 0.001).</p><p><strong>Conclusions: </strong>BAE has to  be taught to the patients with DM in improving the level of LEP and can be encouraged to practice  in the hospital and home care setup. </p>http://ijnmr.mui.ac.ir/index.php/ijnmr/article/view/1724http://ijnmr.mui.ac.ir/index.php/ijnmr/article/download/1724/70707305