Iranian Journal of Nursing and Midwifery Research1735-906626520210901392398ENFaculty of Nursing, MahidolUniversity, Thailand1.Facultyof Nursing, HRH PrincessChulabron College of MedicalScience, Chulaborn RoyalAcademy, Thailand,2.SaintLouis University, TrudyBusch‑Valentine School ofNursing, St.Louis, Missouri,USAAdult Nursing, Faculty ofNursing, Khon Kaen University,Acting Director, Research andTraining Center for EnhancingQuality of Life of Working AgePeople, Thailand2021090420210904<p><strong>Background: </strong>Critically ill patients face challenges in hypercatabolism due to crisis states, as itmay lead to malnutrition. An early Enteral Nutrition (EN) within 24–48 h is recommended to usein order to improve clinical outcomes. This systematic scoping review is examined recently withthe evidence of the early EN protocol led by nurses to drive and achieve the daily calorie targetand improve clinical outcomes.</p><p><strong>Materials and Methods: </strong>The database of CINAHL, MEDLINE viaPubMed and Scopus, Web of Science, and Embase through Ovid from January 2019 to September2020, comprised of 221 articles which four articles are chosen and entered into the final analysis.</p><p><strong>Results: </strong>The findings show the benefits of the early EN to guide nurses to start the EN as soon aspossible after admitted to the Intensive Care Unit or when hemodynamic is stable in order to achievea daily calorie target regarding the reduced hospitalization, duration of mechanical ventilation,morbidity, and mortality. <strong></strong></p><p><strong>Conclusions: </strong>The synthesized results show the early EN led by a nurse toaddress the specific needs and the vital role of nutritional support, and also drive the enteral feedingfor critically ill patients to reach the calorie target goals in short times to enhance clinical outcomes.<strong></strong></p>http://ijnmr.mui.ac.ir/index.php/ijnmr/article/view/1826http://ijnmr.mui.ac.ir/index.php/ijnmr/article/download/1826/70707399