Iranian Journal of Nursing and Midwifery Research1735-906626520210901399405ENStudent Research Committee,Department of CommunityHealth Nursing, School ofNursing and Midwifery,Shahid Beheshti University ofMedical Sciences, Tehran, IranDepartment of CommunityHealth Nursing, Schoolof Nursing & Midwifery,Shahid Beheshti Universityof Medical Sciences, Tehran,IranStudent Research Committee,Department of CommunityHealth Nursing, School ofNursing and Midwifery,Shahid Beheshti University ofMedical Sciences, Tehran, IranStudent Research Committee,Department of CommunityHealth Nursing, School ofNursing and Midwifery,Shahid Beheshti University ofMedical Sciences, Tehran, IranDepartment of BasicSciences, School of Nursingand Midwifery, Shahid BeheshtiUniversity of Medical Sciences,Tehran, Iran2021090520210905<p><strong>Background: </strong>Health literacy (HL) is considered a cancer‑preventive strategy. In addition, successin early diagnosis of cancer largely depends on individuals’ knowledge, attitude, and performanceregarding cancer warning signs. The aim of the present study was to investigate the potentialrelationship between HL and Knowledge, Attitude, and Performance (KAP) regarding cancerwarning signs. <strong></strong></p><p><strong>Materials and Methods: </strong>This descriptive‑correlational study was conducted on 280adults who were referred to 3 health centers in Tehran, Iran, from January to March 2020. Data werecollected using the Health Literacy Instrument for Adults (HELIA) and the researcher‑made KAPregarding cancer warning signs questionnaire. Data were analyzed using the Pearson correlation testand linear regression in an adjusted model in the statistical package for social sciences software.<strong></strong></p><p><strong>Results: </strong>Total HL score was positively and significantly correlated with knowledge (r = 0.35;<em>p </em>&lt; 0.001), attitude (r = 0.17, <em>p </em>= 0.003), and performance (r = 0.46, <em>p </em>&lt; 0.001). Moreover, aftercontrolling for potential confounders, a significant and positive relationship was found betweenHL and knowledge (â = 0.48; t275 = 4.45; <em>p </em>&lt; 0.001), attitude (â =0.17; t265 = 4.64; <em>p </em>&lt; 0.001), andperformance (â = 0.62; t265 = 8.23; <em>p </em>&lt; 0.001). <strong></strong></p><p><strong>Conclusions: </strong>It seems that adults’ KAP regardingcancer warning signs can be promoted by increasing their HL. Therefore, greater attention shouldbe paid to individuals’ HL at community health centers when designing and performing programs toimprove their KAP regarding cancer warning signs.<strong></strong></p><p><strong><br /></strong><em></em><strong></strong></p>http://ijnmr.mui.ac.ir/index.php/ijnmr/article/view/1827http://ijnmr.mui.ac.ir/index.php/ijnmr/article/download/1827/70707400