Iranian Journal of Nursing and Midwifery Research1735-906627220220303163165ENCenter for Research on Occupational Disease, Department of Occupational Medicine, Tehran University of Medical Sciences, Tehran, IranCenter for Research on Occupational Disease, Department of Occupational Medicine, Tehran University of Medical Sciences, Tehran, IranCenter for Research on Occupational Disease, Department of Occupational Medicine, Tehran University of Medical Sciences, Tehran, Iran20220312Background: Several factors play a role in Needlestick Injury (NSI). We aimed to determine the association of NSI with psychomotor performance in health care workers. <br />Materials and Methods: In this cross sectional study, demographic, occupational characteristics, and needlestick history were completed for 357 health personnel of a university hospital of Tehran in 2019 through a checklist. Psychomotor performance was measured using a pursuit aiming test. <br />Results: Most of the NSI occurred in nurses. The mean age of the workers with a positive history of NSI was significantly lower compared to their peers with a negative history, and similarly, they had lower work experience. After adjustment for the confounding variables, the correct pursuit aiming test had a borderline association with the occurrence of the NSI. <br />Conclusions: Psychomotor performance had a borderline association with the history of NSI.http://ijnmr.mui.ac.ir/index.php/ijnmr/article/view/1883http://ijnmr.mui.ac.ir/index.php/ijnmr/article/download/1883/70707457