Iranian Journal of Nursing and Midwifery Research1735-906629620241201649659ENFaculty of Persian Medicine, Herbal and Traditional Medicines Research Center, Department of Traditional Medicine, Kerman University of Medical Sciences, Kerman, IranFaculty of Persian Medicine, Herbal and Traditional Medicines Research Center, Department of Traditional Pharmacy, Kerman University of Medical Sciences, Kerman, IranFaculty of Persian Medicine, Medical Mycology and Bacteriology Research Center, Department of Traditional Medicine, Kerman University of Medical Sciences, Kerman, IranDepartment of Biostatistics and Epidemiology, Faculty of Public Health, Kerman University of Medical Sciences, Kerman, IranSchool of Medicine, Obstetrics and Gynecology Center, Kerman University of Medical Sciences, Kerman, Iran,Department of Biostatistics and Epidemiology, Faculty of Public Health, Kerman University of Medical Sciences, Kerman, Iran,School of Medicine, Department of Pathology and Stem Cell Research Center, Kerman University of Medical Sciences, Kerman, IranFaculty of Persian Medicine, Herbal and Traditional Medicines Research Center, Department of Traditional Medicine, Kerman University of Medical Sciences, Kerman, Iran2024120120241201<p><strong>Background: </strong>Bacterial Vaginosis (BV) is the most prevalent cause of vaginal infection among women. This study aimed to summarize the evidence related to the effectiveness of medicinal plants as an alternative therapy for the management of BV. <strong></strong></p><p><strong>Materials and Methods: </strong>PubMed, Scopus, Cochrane Library, Web of Science, and Medline PubMed were systematically searched. Moreover, we searched Google Scholar to explore the possible effects of herbal treatments on BV in women of childbearing age up to 2022. All randomized clinical trials investigating the effects of medicinal plants as oral or vaginal monotherapy or in combination for BV treatment in women of childbearing age were included in this systematic review.</p><p><strong>Results: </strong>In total, 20 studies comprising 2685 participants were included in our review. The results show that combinations of herbal medicines such as <em>Prangos ferulacea, Berberis vulgaris, Myrtus communis, </em>and <em>Quercus Brantii </em>with metronidazole can have better results in the treatment of BV. Moreover, the main results show that some medicinal plant products alone such as Forzejehe <em>(Tribulus terrestris + Myrtus communis + Foeniculum vulgare + Tamarindus indica), Zataria multiflora, </em>and <em>Calendula officinalis </em>had therapeutic effects similar to metronidazole. Propolis and Brazilian pepper tree <em>(Schinus) </em>were effective in the treatment of BV, but they have less therapeutic effect than metronidazole.</p><p><strong>Conclusions: </strong>To reduce the complications caused by chemical treatments and also the resistance of patients to these treatments, it seems necessary to use supportive treatments along with chemical drugs after the necessary approvals have been obtained.</p><p><strong><br /></strong></p>http://ijnmr.mui.ac.ir/index.php/ijnmr/article/view/2167http://ijnmr.mui.ac.ir/index.php/ijnmr/article/download/2167/70707736