Iranian Journal of Nursing and Midwifery Research1735-906631220260517190194ENDepartment of Nursing, Universitas Diponegoro, IndonesiaDepartment of Nursing, Universitas Diponegoro, IndonesiaSpecialist Programme of Dermatology and Venereology, Universitas Diponegoro, Indonesia2026051320260513<p><strong>Background: </strong>Guided Imagery and Music (GIM) interventions reduced the anxiety in many clinical settings. Traditional music pictures the emotion of specific culture. No interventional study was found in reducing anxiety among ischemic stroke patients using GIM with traditional music. The aim of the study is to determine the effect of GIM with <em>sasando </em>music on anxiety among ischemic stroke survivors. <strong>Materials and Methods: </strong>The method was a quasi‑experimental design with a pretest–post‑test with a control group. Respondents are 50 ischemic stroke survivors divided into two groups and selected by the consecutive sampling technique. The instrument is the HAM‑A questionnaire. The intervention group listened to GIM with Sasando Music from the Nusa Tenggara Timur Province, Indonesia. The statistical test used was the Mann–Whitney test. <strong>Results: </strong>The anxiety score in the intervention group before and after the GIM intervention showed a statistically significant difference, <em>p </em>value = 0.001 (<em>p </em>&lt; 0.05), while in the control group, there was no statistically significant difference, <em>p </em>value = 0.683 (<em>p </em>&gt; 0.05). The test on the two groups showed that there was no significant difference of anxiety score before intervention, <em>p </em>value = 0.351 (<em>p </em>&gt; 0.05). After intervention, there was a significant difference in anxiety score, <em>p </em>value = 0.001 (<em>p </em>&lt; 0.05). <strong>Conclusions: </strong>GIM intervention affects anxiety level on post‑ischemic stroke patients. As a recommendation, GIM can be used as an intervention to reduce anxiety in post‑ischemic stroke patients.</p><p> </p>http://ijnmr.mui.ac.ir/index.php/ijnmr/article/view/2357http://ijnmr.mui.ac.ir/index.php/ijnmr/article/download/2357/70707947