Iranian Journal of Nursing and Midwifery Research1735-906631220260517238245EN1Medical Surgical Nursing Department, Faculty of Nursing, Suez Canal University, Ismailia City, Egypt, 2Department of Medical and Surgical, College of Nursing, Qassim University, Buraydah City, Saudi ArabiaMedical Surgical Nursing Department, Faculty of Nursing, Suez Canal University, Ismailia City, Egypt,1.Medical Surgical Nursing Department, Faculty of Nursing, Suez Canal University, Ismailia City, Egypt, 2.Department of Medical and Surgical, College of Nursing, Qassim University, Buraydah City, Saudi Arabia20260516<p><strong>Background: </strong>Tracheal suctioning is an essential procedure used to maintain airway patency by removing secretions. However, it is a critical nursing skill that carries potential risks. This study aims to evaluate the effects of the dual‑system endotracheal suction on cardiopulmonary function in mechanically ventilated adult patients. <strong>Materials and Methods: </strong>A quasi‑experimental design was employed in this study. A purposive sample of 74 patients was recruited from the intensive care unit of a teaching hospital in the city of Ismailia, Egypt. The patients were assigned to two equal groups, with 37 patients in each group: Group I received closed‑system suction, while Group II received open‑system suction. Data were collected using a single structured tool consisting of three sections: demographic information, health history, and a hemodynamic parameters sheet used to assess cardiopulmonary function before and after suctioning. <strong>Results: </strong>The mean (SD) ages of the studied patients were 49 (6.70) years in Group I and 47.2 (7.10) years in Group II. There was a highly significant difference between the use of closed‑ and open‑suction systems for cardiopulmonary function during (<em>t </em>= 4.23; <em>P </em>= 0.01) and directly postsuction (<em>t </em>= 4.23, <em>P </em>= 0.01). However, no statistically significant differences were observed between the study groups in the presuction phase. <strong>Conclusions: </strong>Patients managed with a closed‑suction system demonstrated improved cardiopulmonary function compared to those who received open suction. Therefore, the use of a closed‑suction system is an effective intervention for minimizing cardiopulmonary instability and supporting the overall well‑being of mechanically ventilated adult patients.</p><p> </p>http://ijnmr.mui.ac.ir/index.php/ijnmr/article/view/2365