Iranian Journal of Nursing and Midwifery Research1735-906616320110724504504ENPhD Student, ICOT University, UK.MSc, Department of Psychiatric Nursing, School of Nursing and Midwifery, Isfahan University of Medical Sciences, Isfahan, Iran.MSc, Department of Psychology, Mana Mehr Novin Co. Isfahan, Iran.PhD, Nursing and Midwifery Care Research Center, School of Nursing and Midwifery, Isfahan University of Medical Sciences, Isfahan, Iran.20110724<ul><li><strong>BACKGROUND</strong><strong>:</strong> Major depressive disorder is one of the most widespread psychological problems in the world. The feelings of a person who is affected by this condition is boring. This article aimed to shed light on the experiences of women with major depressive disorder.</li><li><strong>METHODS</strong><strong>:</strong> A qualitative approach with thematic analysis design has been used to describe the studied phenomenon as experienced by the participants.</li><li><strong>RESULTS</strong><strong>:</strong> Analysis of 92 codes from 12 interviewed participants brought about 4 main themes including loss, inappropriate marital life, cognitive errors, and economic condition.</li><li><strong>CONCLUSIONS</strong><strong>:</strong> This study revealed main concerns of the participants through their life and suggested that psychotherapists should be more sensitive to these aspects of their depress patients' experiences.</li><li><strong>KEY WORDS</strong><strong>:</strong> Major Depressive Disorder, women, qualitative research, psychosocial factors.</li></ul>http://ijnmr.mui.ac.ir/index.php/ijnmr/article/view/504http://ijnmr.mui.ac.ir/index.php/ijnmr/article/download/504/316