The effect of acupressure on muscle cramps in patients undergoing hemodialysis

Kolsoom Mohmadi, Nahid Shahgholian, Mahboubeh valiani, Hossein Mardanparvar



Background: Pain resulting from muscle cramps is one of the most common outcomes of hemodialysis. One of the mechanisms associated with muscle cramps is unnatural muscle metabolism. Because acupressure improves muscle metabolism through the releasing of energy, this study was performed with the purpose of determining the impact of acupressure on muscle cramps.

Materials and Methods: This study was a single-blind clinical trial. Accordingly, 64 patients were selected and intensity and frequency of muscle cramps were determined by randomly categorizing them into two groups. The intervention group received 9 sessions of acupressure and the control group received 9 sessions of placebo intervention. The intervention was performed 15 min before hemodialysis in both groups. In both the groups, average intensity of pain and the frequency pain was compared before, after, and 1 month after completion of the intervention.

 Results: Data analysis revealed that there were no   significant statistical differences between the two groups in terms of mean value of intensity (P = 0.586) and frequency (P = 0.780) of muscle cramps before the intervention. We observed a significant difference after completion of intervention sessions (P < 0.001). Moreover, there were no significant differences between mean value of intensity (P < 0.001) and frequency (P = 0.030) of muscle cramps in the control group before, after, and 1 month after the completion of 9 sessions of placebo intervention.

Conclusions: Employing acupressure may result in decrease of muscle cramps in patients undergoing hemodialysis.



Acupressure; hemodialysis; Iran; muscle cramps

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Oguma S, Ando I, Hirose T, Totsune K, Sekino H, Sato H, et al. Biotin ameliorates muscle cramps of hemodialysis patients: A prospective trial. Tohoku J Exp Med 2012;227:217‑23.

Imani E, Imani A. Assessing Effect of vitamin B1 on side effects on primary Dysmenorrhea. Hormozgan Med J 2008;9:1‑10.

Molaie E, Ghari S, Moujerloo M, Behnampour N, Shariati A, Jafari M, et al. Impact of sodium and ultrafiltration profiling on hemodialysis: Related complications. J Guilan Univ Med Sci 2012;9:11‑9.

Ghafourifard M, Rafieian M, Shahgholian N, Mortazavi M. Effect of linear and stepwise sodium and ultra filtration profiles on intradialytic hypotension and muscle cramps in renal disease patients. J Shahrekord Univ Med sci 2010;12:22‑8.

Tamadon M, Tusi J, Soleimani A, Moqimi J, Malek F, Moradi A, et al. The effect of oral carnitine in reducing complication chronic hemodialysis. YJMS 2008;9:27‑32.

Shahdadi H, Badakhsh M, Msynayy N, Heydari M, Rahnema M. The effect of increasing blood flow rate on complications and dialysis adequacy in hemodialysis patients with low KT/V. J Rostsmineh Zabol Univ Med Sci 2009;17:62‑7.

Chang CT, Wu CH, Yang CW, Huang JY, Wu Ms. Creatine monohydrate treatment alleviates muscle cramps associated with haemodialysis. Nephrol Dial Transplant 2002;17:1978‑81.

Tayyebi A, Savari S, Nehrir B, Rahimi A, Eynollahi B. The effect of vitamin B12 supplementation of fatigue in hemodialysis patients. Iran J Crit Care Nurse 2013;6:39‑48.

Raymond F, Colette B, Lori D. Treatment of leg cramps in patients with chronic kidney disease receiving hemodialysis. CANNT J 2011;25:630‑795.

Yaghoobi M, Amini K, Fathi M, Ahmadi F, Mohammadi E, Salehnejad GH. The effect of massage on pain of muscle cramps in patients undergoing hemodialysis. J Ilam Univ Med Sci 2008;17:1‑8.

Hamidzadeh A, Shahpourian F, Orak RJ. Effect of LI4 acupressure on labor pain in the first stage of labor. Koomesh 2010;12:196‑203.

Husseinabadi R, Norozi K, Pourismail z, Karimlu M, Madah SB. Effect of massage pressure points on sleep quality in elderly. J Rehab 2008;9:8‑14.

Arab Z, Bahrami H, Asayesh H, Vacyli M. Effect of acupressure on the quality of sleep in patient undergoing hemodialysis. J Uremia Nurs Midwifery Fac 2012;10:237‑47.

Snyder M, Linquist R. New York: Springer Publishing Company. ComI Ther Nurs Midwifery 2009;5:58‑66.

Shariati A, Jahani S, Hooshmand M, Khalili N. The effect of acupressure on sleep quality in hemodialysis patients. Complement Ther Med 2012;20:417‑23.

Sabouhi F, Kalani L, Valiani M, Mortazavi M. Effect of acupressure on fatigue in patients on hemodialysis. Iran J Nurs Midwifery Res 2013;18:429‑34.

Kilic Akca N, Tasci S, Karataş N. Effect of acupressure on patients in Turkey receiving hemodialysis treatment for uremic pruritus. Altern Ther Health Med 2013;5:12‑8.

Kim KH, Lee MS, Kang KW, Choi SM. Role of acupressure in symptom management in patients with end‑stage renal disease. J Palliat Med 2010;13:885‑92.

Murigani T, Noble H, McGowan A, Channey M. Dialysis access and the impact on body image: Role of the nephrology nurse. Br J Nurs 2008;17:362‑6.

Ozdemir G, Ovayolu N, Ovayolu O. The effect of reflexology applied on haemodialysis patients with fatigue, pain and cramps. Int J Nurse Pract 2013;19:265‑73.

Karimipour F, Fayazi S, Mowla K, Latifi M. Effect of acupressure on severity of pain in arthritis rheumatoid patients. Sci Med J Ahwaz Jundishapur Univ Med Sci 2012;11:269‑75.

Hosseini A. Acupressure. First Edition. Publication Babazade. By Askayy A 2012:16‑28

Bazarganipour F, Lamyian M, Ahmari TH, Heshmat R, Asghari JM. Evaluation of the effect Liv3 acupressure on severity and duration of primary dysmenorrhea. Knowl Health 2010;5:27‑35.

Hsu WS, Shen XY, Yang JM, Luo L, Zhang L, Qi DD, et al. Effects of acupuncture applied to sanyinjiao with different stimuli on uterine contraction and microcirculation in rats with dysmenorrhea of cold coagulation syndrome. Evid Based Complement Alternat Med. 2014;2014:328657.

Lee MK, Chang SB, Kang DH. Effect of SP6 acupressure on labor pain and length of delivery time in women during labor. J Altern Complement Med 2004;5:959‑65.

Salsali M, Pouresmaeil Z, Faghiehzadeh S, Sepahvand F. Effect of acupressure on low back pain. Hayat 2003;9:52‑62.

Bastani F, Sobhani M, Bozorgnejad M, Shamsikhani S, Haghani H. Effect of acupressure on severity of pain in women with multiple sclerosis. Complement Med J Fac Nurs Midwifery 2012;2:75‑84.

Masoudi N, Atai M, Mohammadi M, Alirezaei M, Shafie M, Abbaszade H. Effect of acupressure on pain of intramuscular injection. Quart J Grace 2007;11:14‑8.

Gharelghi SH, Tork SH, Heshmat R, Akbarzadeh A. The effect of acupressure at Sanynjyv (sp6) and DJ (sp8) on the severity of primary dysmenorrhea. Behbood J 2011;15:245‑50.

Kashefi F, Ziyadlou S, Fadaee A, Ashraf A, Jafari P. The effect of sp6 acupressure on primary dysmenorhea in medical university students in Birjand. J Iran Univ Med Sci 2009;16:102‑10.

Kim JS, Jo Y, Hwang SK. The effects of abdominal meridian massage on menstrual cramps and dysmenorrhea in full‑time employed women. Taehan Kanho Hakhoe Chi 2005;35:1325‑32.

Yeh CH, Morone NE, Chein LC, Cao Y, Lu H, Shen J, et al. Auricular point acupressure to manage chronic low back pain in older Adult. J Evid Based Complement Alternat Med 2014;2014:375173.


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