Severe Ovarian Hyperstimulation Syndrome in A Spontaneous Pregnancy with Normal Singleton Fetus: A Case Report

Zahra Rastin, Nayereh Ghomian, Majid Khadem‑Rezaiyan

Abstract


Most cases of Ovarian Hyperstimulation Syndrome (OHSS) are associated with the use of exogenous gonadotropins for the induction of multiple oocytes. However, OHSS is rarely associated with a spontaneous ovulatory cycle in women with multiple gestations, hypothyroidism, polycystic ovary syndrome, or molar pregnancies. Herein, we report a case of OHSS in a woman with spontaneous pregnancy, without any underlying diseases or risk factors. The clinical findings showed abdominal pain, nausea, dyspnea, and amenorrhea. After imaging and laboratory tests, the final diagnosis was established. The patient was managed successfully without any complications. In conclusion, although spontaneous ovarian hyperstimulation is a rare condition, physicians should be able to diagnose this condition. In fact, early diagnosis and successful management can potentially prevent serious complications, which are likely to develop rapidly in patients

Keywords


Fetus, ovarian hyperstimulation syndrome, pregnancy

Full Text:

PDF

References


Kasum M, Orešković S, Ježek D. Spontaneous ovarian hyperstimulation syndrome. Coll Antropol 2013;37:653‑6.

Alper MM, Smith LP, Sills ES. Ovarian hyperstimulation syndrome: Current views on pathophysiology, risk factors, prevention, and management. J Exp Clin Assist Reprod 2009;6:3.

Sansone P, Aurilio C, Pace MC, Esposito R, Passavanti MB, Pota V, et al. Intensive care treatment of ovarian hyperstimulation syndrome (OHSS). Ann N Y Acad Sci 2011;1221:109‑18.

Cabar FR. Ovarian hyperstimulation syndrome in a spontaneous singleton pregnancy. Einstein (Sao Paulo, Brazil) 2016;14:231‑4.

Kim SJ, Yoon JH, Kim HK, Kang HC. Spontaneous ovarian hyperstimulation syndrome in a young female subject with a lingual thyroid and primary hypothyroidism. Korean J Intern Med 2016;32:559‑62.

Lovgren TR, Tomich PG, Smith CV, Berg TG, Maclin V. Spontaneous severe ovarian hyperstimulation syndrome in successive pregnancies with successful outcomes. Obstet Gynecol 2009;113:493‑5.

Oztekin O, Soylu F, Tatli O. Spontaneous ovarian hyperstimulation syndrome in a normal singleton pregnancy. Taiwan J Obstet Gynecol 2006;45:272‑5.

Vloeberghs V, Peeraer K, Pexsters A, D’Hooghe T. Ovarian hyperstimulation syndrome and complications of ART. Best Pract Res Clin Obstet Gynaecol 2009;23:691‑709.

Rachad M, Chaara H, Zahra Fdili F, Bouguern H, Melhouf A. Ovarian hyperstimulation syndrome in a spontaneous pregnancy with invasive mole: Report of a case. Pan Afr Med J 2011;9:23.

Davis M, Kennedy R. Ovarian hyperstimulation syndrome: Aetiology, prevention and management. Rev Gynaecol Perinatal Pract 2006;6:26‑32.

Taher BM, Ghariabeh RA, Jarrah NS, Hadidy AM, Radaideh AM, Ajlouni KM. Spontaneous ovarian hyperstimulation syndrome caused by hypothyroidism in an adult. Eur J Obstet Gynecol Reprod Biol 2004;112:107‑9.

Arora R, Merhi ZO, Khulpateea N, Roth D, Minkoff H. Ovarian hyperstimulation syndrome after a molar pregnancy evacuation. Fertil Steril 2008;90:1197.e5‑7.

Davoudian P. Placental mesenchymal dysplasia associated with spontaneous ovarian hyperstimulation syndrome. BMJ Case Rep 2015;2015. doi: 10.1136/bcr‑2014‑207420.

Chae HD, Park EJ, Kim SH, Kim CH, Kang BM, Chang YS. Ovarian hyperstimulation syndrome complicating a spontaneous singleton pregnancy: A case report. J Assist Reprod Genet 2001;18:120‑3.


Refbacks

  • There are currently no refbacks.