Adherence to Medication and Physical Activity among People Living with HIV/AIDS

Mohammad-Ali Morowatisharifabad, Ehsan Movahed, Rohollah Nikooie, Jamileh Farokhzadian, Reza Bidaki, Mohsen Askarishahi, Mahdieh Hosseinzadeh


Background: The aim of this study was to investigate the adherence to medication and Physical Activity (PA) among People Living with HIV (PLHIV).

Materials and Methods: In the present cross‑sectional study, 122 PLHIV were selected. The research tools included the Baecke questionnaire and the AIDS Clinical Trials Group questionnaire. Data were analyzed by independent t test and multiple logistic regression.

Results: The results of 7‑ and 30‑day recalls showed that 76.21 and 82.23% of patients had proper medication adherence. The mean score of PA in patients was less than the recommended average score in the questionnaire. Furthermore, there was no significant difference observed between the medication adherence and PA.

Conclusions: Although the adherence to medication was appropriate, nurses and health care providers should increase the level of PA for PLHIV by dealing with the related barriers to live an active life.


Exercise, HIV infections, Iran, medication adherence

Full Text:



Gao Y, Kraft JC, Yu D, Ho RJY. Recent developments of nanotherapeutics for targeted and long‑acting, combination HIV chemotherapy. Eur J Pharm Biopharm 2019;138:75‑91.

Gholamaliei B, Karimi‑Shahanjarini A, Roshanaei G, Rezapour‑Shahkolaei F. Medication adherence and its related factors in patients with Type II diabetes. J Educ Community Health 2016;2:3‑12.

Nyamathi A, Ekstrand M, Heylen E, Ramakrishna P, Yadav K, SinhaS, et al. Relationships among adherence and physical and mental health among women living with HIV in rural India. AIDS Behav 2018;22:867‑76.

Daryazadeh S. Investigation of adherence and process of anti‑retroviral therapy in patients referred to Isfahan behavioral consultation center during ten years. Razi J Med Sci 2014;21:62‑70.

Chapman SB, Aslan S, Spence JS, De Fina LF, Keebler MW, Didehbani N, et al. Shorter term aerobic exercise improves brain, cognition, and cardiovascular fitness in aging. Front Aging Neurosci 2013;5:75.

Vancampfort D, Mugisha J, De Hert M, Probst M, Firth J, Gorczynski P, et al. Global physical activity levels among people living with HIV: Asystematic review and meta‑analysis. Disabil Rehabil 2018;40:388‑97.

Brawner BM. Attitudes and beliefs regarding depression, HIV/AIDS, and HIV risk‑related sexual behaviors among clinically depressed African American adolescent females. Arch Psychiatr Nurs 2012;26:464‑76.

Baecke JA, Burema J, Frijters JR. A short questionnaire for the measurement of habitual physical activity in epidemiological studies. Am J Clin Nutr 1982;36:936‑42.

Kekwaletswe CT, Jordaan E, Nkosi S, Morojele NK. Social support and the mediating roles of alcohol use and adherence self‑efficacy on antiretroviral therapy (ART) adherence among ART recipients in gauteng, South Africa. AIDS Behav 2017;21:1846‑56.

Elul B, Basinga P, Nuwagaba‑Biribonwoha H, Saito S, Horowitz D, Nash D, et al. High levels of adherence and viral suppression in a nationally representative sample of HIV‑infected adults on antiretroviral therapy for 6, 12 and 18 months in Rwanda. PLoS One 2013;8:e53586.

Pellowski JA, Kalichman SC. Health behavior predictors of medication adherence among low health literacy people living with HIV/AIDS. J Health Psychol 2016;21:1981‑91.


  • There are currently no refbacks.