An investigation into the factors effective in the consent of families with brain‑dead patients candidates for organ donation in Isfahan, Iran in 2012‑13

Maryam Khalifehsoltani Khajooei, Fereshteh Zamani, Asieh Maghami Mehr


Background: Studies have shown that, with regard to social, cultural, and institutional contexts, several factors affect family decision-making on organ donation. This study aimed to investigate the effective factors in organ donation by family members
with brain-dead patients.
Materials and Methods: This was a descriptive-comparative study in which a researcher-made questionnaire was used to collect data. The reliability of the questionnaire was obtained as 0.81 using Cronbach’s alpha. The study sample consisted of 85 members of families with brain-dead patients in Isfahan, Iran in 2012–13. The collected data were analyzed using the Statistical Package for the Social Sciences version 20.0, and the level of significance was considered as <0.05.
Results: The obtained results indicated that factors such as age, marital status, level of education, and cause of brain death did not have any effect on their families consent, whereas factors such as gender, duration of hospitalization, having an organ donation card, personal view of the brain‑dead patient, and the number of patient’s children had a significant relationship with the consent on organ donation. In addition, the care and treatment team were effective in family decisions regarding organ donation.
Conclusions: In general, the necessary culture and increasing the population awareness and their knowledge can be a positive step in this regard and may bring about an easy and rapid acceptance of organ donation by the involved families.


Brain death; family consent; Iran; organ donation

Full Text:



Brain death and organ harvesting of the language of with verses and hadiths. J Borhan and Mysticismd 2006;7:171-86.

Yousefi H, Roshani A, Nazari F. Experiences of the families concerning organ donation of a family member with brain death. Iran J Nurs Midwifery Res 2014;19:323‑30.

Mori K, Shingu K, Nakao S. Brain Death in Miller RD, Millers Anesthesia. 6th edition, Philadelphia: Elsevier; 2005. pp. 2955‑70.

Wayne P. Organ transplantation. Prog Transplant 2010;20:274‑8.

Smeltzer SC, Brenda B, Hinkle JL, Cheever KH. Brunner and Suddarth’s Textbook of Medical-Surgical Nursing (One Volume Set). 12th ed. Philadelphia; 2010. p. 2240.

Motavali Zadeh S, Kiani SH. Brain death and organ donation. Tehran: Charity Foundation for Special Diseases, published research, education and agricultural extension agencies, 2007.

Linda D, Kathleen M, Mary E. Critical Care Nursing. 6th edition. Elsevier eBook on VitalSource; 2010. Pp. 1206.

Manzari Z, Mohammadi A, Heidari A. Factors influencing family decisions about organ donation in brain dead patients: A qualitative study. Payesh J 2012;6:913‑25.

Margot E, Capland C, Dionne J, Fudge B, Gay C. A clinical groups attempt to raise awareness of organ and tissue donation. J Prog Transplant 2010;20:33‑9.

Ghadi Pasha, Nikian M, Tajodin Z. Evaluate the attitude and awareness of organ donation in brain death etiquette and procedure. J Forensic Med 2008;2:112‑6.

Zamani F, AbediHydar Ali. A comparative study on effective factors on consent to organ donation among families of brain death victims in Isfahan, 2013. J Emerg Pract Trauma 2015;1:13‑8.

Abouna GM. Organ shortage crisis: Problems and possible solutions. J Transplant Proc 2008;40:34‑8.

West R, Burr G. Why families deny consent to organ donation. Aust Crit Care 2002;15:27‑32.

James R, Danielle L, Jennifer K, Richard J. Family Initiated Discussions about Organ Donation at the Time of Death. Clin Transplant 2010;24:493‑9.

Kim JR, Elliott D, Hyde C. The influence of sociocultural factors on organ donation and transplantation in Korea: Findings from key informant interviews. J Transcult Nurs 2004;15:147‑54.

Siminoff LA, Lawrence RH, Arnold RM. Comparison of black and white families’ experiences and perceptions regarding organ donation requests. Crit Care Med 2003;31:146‑51.

Rice C, Tamburlin J. A confirmatory analysis of the organ donation readiness index: Measuring the potential for organ donation among African Americans. Res Soc Work Pract 2004;14:295‑303.

Traino HM, Siminoff LA. Attitudes and acceptance of First Person Authorization: A national comparison of donor and nondonor families J Trauma Acute Care Surg 2013;74:294‑300.

Shahbazian H, DibaeiA, Barfi M. Public attitudes toward cadaveric organ donation: A sSurvey in Ahwaz. Urol J 2006;4:234‑9.

Shamsi A, Alizadeh Charandabi S. Compare opinions and refuse to families of brain dead patients degree of understanding of the underlying factors related to organ donation decision. Thesis for obtaining a master’s nursing education, 2008;16:1-150. [Persian].

Boroumand MA, Asghari F. Relatives of organ donation after brain death, whether people agree with Tehran? J Med Ethics Hist Med 2011;5:52‑8.

Siminoff LA, Gordon N, Hewlett J, Arnold RM. Factors influencing families’ consent for donation of solid organs for transplantation. JAMA 2001;286:71‑7.

Delmonico FL, Sheely E, Marks WH, Baliga P, McGowan JJ, Magee JC. Organ donation and utilization in the United States, 2004. Am J Transplant 2005;5:862‑73.

Manzari ZS, Mohammadi E, Heydari A, Sharbaf HR, Azizi MJ, Khaleghi E. Exploring families’ experiences of an organ donation request after brain death. Nurs Ethics 2012;19:654‑65.

DeJong W, Franz HG, Wolfe SM, Nathan H, Payne D, Reitsma W, et al. Requesting organ donation: An interview study of donor and non‑donor families. Am J Crit Care 1998;7:13‑23.

Bormand MA, Asghari F. Do Tehran citizens agree with organ donation from a brain‑dead family member? J Med ethics Hist Med 2011;5:51‑8.

Burroughs TE, Hong BA, Kappel DF, Freedman BK. The stability of family decisions to consent or refuse organ donation: Would you do it again. Psychosom Med 1998;60:156‑62.

Maloney G, Walker I. Messiahs, pariahs, and donors: The development of social representations of organ transplants. J Theory Soc Behav 2000;30:203.

Arjmand B, Aghayan HR, Godarzi P, Emami Razavi H, Ja’farian A. Knowledge and attitudes about organ donation and tissue donation card makers and members of connective tissue bank products (case/control). J Med Council Islamic Republic Iran 2008;26:30‑5.


  • There are currently no refbacks.