COVID19 Vaccination Considerations for Pregnant Women: A Systematic Review
Abstract
Abstract
Background: Following the coronavirus disease 2019 (COVID‑19) pandemic, pregnant women are at a higher risk of developing severe COVID‑19 disease. This study investigated whether pregnant women should get vaccinated against COVID‑19 or not. Pregnant women in comparison with non‑pregnant women.
Materials and Methods: This study was a systematic review that searched the PubMed, Embase, and Scopus databases using the keywords “COVID‑19” OR “SARS‑CoV‑2” OR “Coronavirus Disease” OR “2019‑nCoV” AND “pregnancy “OR “pregnant” AND “vaccine” OR “vaccination” from January 2020 to April 2022.
Results: Of the 37 selected studies, 15 (40.50%) declared positive views, 9 (24.30%) had inconclusive views, and 13 (35.20%) opposed vaccination due to a lack of adequate information.
Conclusions: Despite the discrepancies among the studies, one‑third of the studies suggested that pregnant women be enrolled in clinical trials to investigate the outcomes of the COVID‑19 vaccination on maternal and fetal outcomes. However, the majority of the studies recommended maternal immunization against COVID‑19.
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